This is a quote from the book "The ​Virtue Of Selfishness" by Ayn Rand
... possibility of defeat. He knows also that there is no alternative and no automatic guarantee of success for man’s effort, neither in dealing with nature nor with other men. So he does not jud ge his interests by any particular defeat nor by the range of any particular moment. He lives and judges long-range. And he assumes the full responsibility of knowing what conditions are necessa ry for the achievement of his goals.

(c) Responsibility. This last is the particular form of intellectual responsibility that most people evade. That evasion is the major cause of ...
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